This study is aimed at investigating the perceptions of the teachers of English in Can Tho University (CTU) on Blended learning (BL). This research brings a practical assessment on the feasibility of this approach at the tertiary level. The study is composed of mixed methods of an online questionnaire and an informal interview. Participants were 136 students and 16 teachers currently working in CTU, one of the oldest and biggest universities in Vietnam. The findings of the study show the teachers’ appreciation of the approach and their awareness of its leverage in future teaching practice. However, it is still too early to conclude that this approach will soon replace traditional teaching methods in physical rooms. Therefore, it is recommended that further research on BL should be done to ensure its validity and explore its effectiveness in a Vietnamese context, especially under the impact of Covid-19 pandemic.Mju