Distance learning for self-learning is the main task, so learning material in distance learning compared to traditional training plays a more important role, It is considered one of the most critical success factors in the learning process of distance learning. Therefore, the prerequisite of distance learning is to have sufficient separate learning resources for distance learning. The training materials of distance education must be both scientific and moderately suitable for learners of distance. In ths article, the author analyzes and clarifies the current, direction of improving the effectiveness of compiling and using distance learning training materials at universities in the form of distance learning in general an Can Tho University in particular.