This paper focuses on analysing the factors affecting the librarianship students’ participation in scientific research in Can Tho University. The research is based on the conceptual framework and the State's regulations related to scientific research among students. Data collected in this study was a survey of 137 current librarianship students.  The findings show that passion, external motivation and self-interest were the factors influencing students' participation in scientific research. In particular, the benefits of scientific research were found to be the most powerful factors that motivate students to conduct research. However, low awareness of self-study was reported as the factor hindering students from participating in scientific research activities. These findings provide insights into the true value of research activities among students for the Department of Information and Library Management, the Faculty of Social Sciences and Humanities, and other training units in a university in the Mekong Delta.