A study was conducted at the experimental farm and laboratory of Can tho University to evaluate feed utilization, growth performance and economic return of Crossbred rabbits (New Zealandx local). The experiment was a factorial design in which the first factor was feeding method (Separate and mix) and second factor was the levels of Centrocema pubescens : Para grass (20:80, 40:60, 60:40 and 80:20), with three replications and 4 rabbits per experimental unit. The results indicate that values of dry matter (DM), crude protein (CP), ether extract (EE), neutral detergent fiber (NDF), acid detergent fiber (ADF), metabolizable energy (ME) intakes were significantly higher (PCentrocema pubescens in the diets. The daily weight gain, weight of carcass, and thigh meat of rabbits fed separated feeds and the level of 80:20  Centrocema pubescens and Para grass had the highest results (PCentrocema pubescens andPara grass had better growth performance and gave higher economic efficiency.