The extensive general education program introduced in 2018 is currently being rolled out across all levels of education, and it has proven to bring forth a myriad of benefits by seamlessly integrating the STEM education model into various subjects and topics. It intends to conduct a comprehensive examination into the present status of STEM teaching practices within educational institutions in the Mekong Delta, alongside an in-depth assessment of teachers’ proficiency in employing active teaching methodologies and practical STEM pedagogical approaches. The results obtained show that teachers use many different teaching methods and techniques to apply to STEM lessons, but these methods and techniques still lack uniformity and standardization in application. When evaluating the responses of the 30 participating teachers, it became clear that traditional teaching methods and techniques were more popular than modern methods. This trend may be due to the need to accommodate different objective factors to tailor the choice of methods and techniques to different groups of students.