The study was carried out with the objective of assessing the ambient air quality in Tien Giang province in 2022. Compared with the National Technical Regulation on Ambient Air Quality (QCVN 05:2013/BTNMT), the value of the component pollution parameters (TSP, CO, NO₂, SO₂) are all within the allowable limits. In particular, in Tien Giang province, O₃ was not detected. From the average value at 34 monitoring locations, CA has grouped 10 clusters of locations with similar air quality (Euclid=1.5). At the same time, 05 monitoring periods are also grouped into 3 clusters. The mean difference between the TSP, CO, NO₂ and SO₂ parameters was also recorded by One way ANOVA analysis. Pearson correlation showed that TSP and PM₁₀ parameters have weak and moderate correlation with CO, NO₂ and SO₂ parameters. Meanwhile, a strong correlation was noted between TSP and PM₁₀ as well as CO, NO₂ and SO₂. Remarkably, the results of PCA analysis recorded a positive contribution of CO, NO₂ and SO₂ parameters in PC1, while TSP and PM₁₀ significantly contributed to PC2. These are considered two sources of pollution related to industrial activities and traffic activities.