The study was carried out to assess groundwater quality in Hau Giang province in the period of 2017-2019. Groundwater quality data was collected at 8 monitoring stations, each with 3 boreholes with the frequency of two times per year.  Groundwater samples were analyzed for criteria of pH, Fe, SO₄^2-, N-NO₂^-, N-NO₃^-, hardness, N-NH₄⁺, Cl^- and permanganate. Each parameter was evaluated using national technical regulation on groundwater quality (QCVN 09-MT:2015/BTNMT). The results showed that the indicators of pH, SO₄^2- and N-NO₃^- did not exceed the allowable thresholds of the regulation; Fe, N-NO₂^-, N-NH₄⁺, Cl^- and permanganate sometimes exceeded the permissible limits by 1.4-2.4, 1-3.43, 1.04-2.99, 1.01-4.1, 1.25-16.41, 1.72-4.07 times, respectively. The main causes of groundwater quality degradation could be from agricultural activities, and geological characteristics. More attention needs to be paid for managing the groundwater quality in Hau Giang province.