This research was implemented to assess the current status of pesticide utilization and management in Chau Thanh A and Long My districts, Hau Giang province The study was conducted by interviewing 60 households, which have 2 crops and 3 crops per year in agricultural cultivation. The results showed that farmers in the two-rice crop model used the right pesticides at the right dose, only 3.33% used the lower doses. In contrast, 36.67% of farmers in the three-rice crop model used pesticides at higher doses than the prescribed and 63.33% of the farmers used the right doses. The toxicity of the pesticides in the three crop rice model was found to be lower than that of the two crop rice model. More diverse types of pesticides were applied in the three-rice crops model. The percentages of the farmers concerned of the harmful effects of pesticides in the two-rice and three-rice crops were 100% and 73.33%, respectively. The main methods to handle the used bottles of pesticides were burial, burning, store, and selling to the vendors. In this study indicated that awareness of the interviewed farmers in the area of ​​two-rice crop regarding use, management and understanding of harmful effects of pesticides was better than those in the three-rice crop cultivating area. The local environmental managers should continually propagate to farmers of knowledge of selection, use and management of pesticides, especially, the farmers in the three-rice growing area to protect health and prevent environmental pollution.