The objective of the study is to identify the demand for information technology (IT) in business administration. Research data were collected by quota sampling with a sample size of 446 enterprises in Can Tho City. The results have pointed out factors that positively affect IT adoption in the management of enterprises including manager qualifications, labor quality, policies, competition, and the scale of customers and partners. Applying the logistic regression, the study has provided assumptions about the probability of IT adoption in business management: if the enterprise has high-quality labor resources, high-qualified managers, supportive policies, a large scale of customers and partners, and a high level of competition, the enterprise has high probability to apply IT in management. Among these, labor quality has the most influence on the demand for IT adoption in business management in Can Tho City.