The purpose of this study is to assess the actual status and recommend some solutions to improve the efficiency of physical education (PE) work at Can Tho University. By synthesizing documents, interviewing and processing statistics, the article has assessed the actual status of PE work through the following aspects: the actual status of training; the actual status of teacher development; the actual status of the organization of sports activities, the actual status of the facilities and the actual status of the scientific research in the field of sports at Can Tho University. At the same time, the study also proposes 5 groups of solutions corresponding to the above status, which have been approved by the Board of Directors and unit members in the medium-term plan of the Department of Physical Education of Can Tho University