The study aims to determine the effects of alkalinity on the growth and survival rate of white leg shrimp (Litopenaeus vannamei) at salinity of 2 ppt. The experiment was set up in five treatments (alkalinity of 40, 80, 120, 160, and 200 mg CaCO₃/L), with three replicates. The shrimp (0.05 g body weight) were stocked at density of 200 shrimp/m³ in the 0.5-m³ tanks, and fed with 4 times per day using commercial feed (35% protein, ad libitum). After 3 months rearing, the shrimp growth rates of treatments 120 and 160 mg CaCO₃/L (0.130 and 0.127 g/day, respectively) were significantly higher than (p3 treatment, respectively). The shrimp survival rate of treatment 120 mg CaCO₃/L (59.3%) was significantly higher than (p3/L.