In developing countries like Vietnam, economic development is closely linked to urbanization speed. This reality puts urban managers on the challenges of managing and orienting for urban development. Thus, understanding the urban growth will help the managers to build the urbanization plans. This study focused on developing an urban growth model where the cities are divided by complex canals in the Mekong Delta of Vietnam. The model was built with the GAMA platform based on the agent-based modeling approach. In the model, urban development is examined according to some urban development criteria such as the built-up density index, the proximity index of the administrative center, and the infrastructure criteria such as the distance from an available cell to the roads and to the residential areas;the location of cell in separated area by rivers and canals. The model was calibrated and was verified with the urban maps in 2017 of Nga Bay Town of Hau Giang province, Vietnam.