A total of 140 weaned piglets (Duroc x Yorkshire-Landrace) with the initial live weight of 15.0±0.17 kg, was allotted into 7 treatments and 4 replications in a completely randomized design. Control (C): Basal diet, complete feed was mixed by the farm (no probiotic adding). Probiotic 1 (Pediococcus acidilactici, 10¹⁰-10¹¹ CFU/g) (PA). Probiotic 2 (Pediococcus acidilactici 10¹⁰-10¹¹ CFU/g + Saccharomyces cerevisiae 10⁹-10¹⁰ CFU/g) (PA+SC). Probiotic 3 (Pediococcus acidilactici 10¹⁰-10¹¹ CFU/g + Bacillus subtilis 10⁹-10¹⁰ CFU/g) (PA+BS). Two ways of feeding offered (1) pigs fed by constant feeding and (2) pigs fed as an part of feeding. Results showed that the final live weight (kg/head) and daily weight gain (g/head/day) of pigs among treatments were significantly different (PFCR was lowest in PA + SC (1) and highest in the control (PE. coli bacteria in the pigs’ feces at the time of 30; 45 and 60 days were significantly different...