An experiment was conducted to evaluate the interactive influences of dietary ME and lysine on growth of H’mong broilers from 0 to 28 day of age. The study was in a 3x3 two-factorial design, with the first factor being 3 levels of ME (3,000; 3,100; and 3,200 kcal/kg of feed) and the second one being 3 levels of lysine (1.1%; 1.0%; and 0.9%), and 4 replicates with 6 broilers for each. Two hundreds and sixteen broilers were placed into 36 bamboo floor pens (6 birds/pen). The diets were formatted from corn yellow, soybean meal, soybean oil, DCP, shell, mineral and vitamin premixes, salt, and some of synthetic essential amino acids. Chicks were fed ad libitum and provided water all of time. The feeding trial was lasted for 4 weeks. The result indicated that the ME 3,000 kcal/kg of feed and lysine 1.1% diet resulted the most efficient FCR