Constructed floating wetlands (CFWs) have emerged as a promising ecological engineering tool for the restoration of water bodies and have been extensively studied in controlled environments such as mesocosms and laboratories. There is a lack of in situ applications to improve ecosystem health. To address this gap, the project CRRP2021-06MY-Jegatheesan, funded by the Asia-Pacific Network for Global Change Research (APN-GCR), was undertaken. As part of this project, six CFWs were installed in 2022 at Bung Xang Canal in Can Tho City, Vietnam, by the College of Environment and Natural Resources (CENREs) at Can Tho University (CTU). The guide synthesises the knowledge gathered and provides an overview of the operating principles of CFWs. Detailed information on installation, including the official procedure, plant selection, and location, is also included in the guide. Moreover, the guide addresses the challenges that may arise during maintenance and offers recommendations and solutions to ensure the smooth operation of CFWs. The guide is expected to serve as a valuable resource for practitioners and researchers involved in the design, installation, and operation of CFWs for specific water resource management purposes and aims to promote the wider implementation of CFWs and contribute to sustainable management and restoration of water bodies.