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Tạp chí quốc tế 2024
Số tạp chí 14(2024) Trang: 1877-1877
Tạp chí: Characterization and molecular identification of the lumpy skin disease virus in cattle in the Mekong Delta of Vietnam
Background: Lumpy skin disease (LSD) is caused by a virus belonging to the genus Capripoxvirus, exhibiting clinical
symptoms ranging from mild signs to the development of nodules. LSD emerged in Asia and Southeast Asia, including
Vietnam, in October 2020 and has since spread throughout the region, resulting in productivity and economic losses.
Aim: This study aimed to investigate the virus-causing papular dermatitis in cattle from the Mekong Delta region
of Vietnam by analyzing its GPCR gene and assessing its evolutionary relationship with sequences in the GenBank
database.
Methods: Blood samples (n = 180) were collected from cattle farms in Ben Tre, Tien Giang, and Tra Vinh provinces.
PCR targeting the P32 antigen gene was utilized to detect LSDV presence, and GPCR gene amplification was performed
to assess genetic variability.
Results: LSDV was detected in 8.33% (15/180) of the samples using PCR targeting the P32 antigen gene. Each sample
that tested positive for LSDV demonstrated complete amplification of the GPCR gene. Sequence alignments and
phylogenetic analyses of the GPCR gene revealed that Mekong Delta LSDV isolates shared genetic similarities and
possessed a 12-nucleotide insertion comparable to strains from China in 2019 and Northern Vietnam in 2020.
Conclusion: This study provides preliminary insights into the molecular characteristics of LSDV in cattle from the
Mekong Delta region of Vietnam. The observed genetic relatedness to other LSDV sequences from Asia and Southeast
Asia underscores the importance of regional surveillance and control measures. These findings contribute to the
development of effective strategies for LSDV control and prevention.
Keywords: GPCR, Lumpy skin disease virus, Characterization, Mekong Delta, Vietnam.
Các bài báo khác
Số tạp chí 68(2024) Trang: 543-548
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Số tạp chí 51(2024) Trang: 82-91
Tạp chí: Journal of Hunan University Natural Sciences
Số tạp chí 56(2024) Trang: 474-488
Tạp chí: Journal of Engineering and Technological Sciences
Số tạp chí 4(2024) Trang: 1-12
Tạp chí: The 4th International Conference on Innovations In Social Sciences Education and Engineering (ICoISSEE-4)


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