This study assessed the surface water and groundwater quality in swine burial pits infected with African swine fever in An Giang province. Data of surface water quality were collected from the Department of Natural Resources and Environment of An Giang province with 10 monitoring positions (denoted S1 to S10) in 3 times (March, June and September) in 2020. The groundwater quality data was collected at 6 locations including S1, S3, S4, S6, S8 and S10. Parameters for surface and ground water quality including chemical oxygen demand (COD), biological oxygen demand (BOD), nitrite (NO₂^--N), nitrate (NO₃^--N), orthosphosphate (PO₄^3--P), ammonium (NH₄⁺-N), coliform and E. coli were examined. Surface water quality was evaluated using QCVN 08-MT:2015/BTNMT while groundwater quality was assessed using QCVN 09-MT:2015/BTNMT.  The findings showed that all of the surface water variables exceeded the limits of QCVN 08-MT:2015/BTNMT, column B1, except NO₃^--N. This indicated that surface water quality in these monitoring sites were polluted by organic matters, nutrients and microbes. It was als found that coliform and E. coli densities in ground water samples were very high. The findings of the present study revealed that water quality in swine burial pits infected with African swine fever in An Giang province was seriously polluted especially with coliform and E. Coli which could pose adverse risk to surrounding environments and health. Alternative method should be used for the treatment of swine death due to African swine fever to curb the water pollution problems