The results of study about medicinal plant resource of Giong Rieng district in Kien Giang province has classified 383 species belonging to 287 genera of 103 families in 3 phylla using for making medicine. In which, there were 3 species which are listed in the “Vietnamese Red Book” (2007) and the Government Decree 32/G/2006. The major life form of the medicinal plants to be surveyed was the grass group with 183 species, making 47.78%. The medicinal plants to be surveyed were arranged in five kinds of ecological places, in which the most acheivement was in the home garden, the orchard with 306 species, making up 79.90%. The medicinal plants to be surveyed can prevent and treat 22 disease groups.