This study was conducted to evaluate the effects of glucose supplementation into seawater to preserve juvenile blood cockles to maintain good health conditions and high survival rate during seed transportation. Blood cockle at small (SL: 9.73 ± 0.95 mm) and big size (SL: 15.85 ± 1.04 mm) were laid into the plastic baskets (12 ind./basket, 3 baskets/treatment) and sprayed with seawater 25‰ (SW) or SW adding glucose with different concentrations of 50, 75 and 100 mg/L during 5 days of preservation. Our findings showed that the highest survival rate was obtained in small cockles were sprayed with SW+100 mg/L glucose (91.6%) and big cockles with SW+50 mg/L glucose (36.1%). Percentage of weight losses during preservation was not significant difference among treatments within size class (P>0.05). After 21 days of cultured period, survival rate of small cockles (75.5-80.6 %) which spraying before with SW+ glucose at 50, 75 and 100 mg/L were significantly higher than those from normal SW (P.