Action research has become a popular career development tool for teachers around the world and has begun to gain the attention of researchers in Vietnam. Courses in English for Specific Purposes (ESP) are receiving a lot of attention in a variety of disciplines, especially in Vietnamese universities. Action research can provide teachers with the necessary skills and knowledge to influence change positively in the classroom, school and community (Johnson, 2012; Stringer, 2008). This paper aimed to identify the students’ perception of action research in improving the quality of teaching and learning ESP in Can Tho University (CTU). Data research were collected from 200 students at CTU who learned ESP of Sociology, Tourism, Economics, Information Technology, Aquaculture and Agriculture by direct interviews. The descriptive statistical method was used in the study to analyze the students’ perception of the AR as well as applying the AR in improving the quality of teaching and learning ESP. Research resutls showed that CTU students have professional knowledge on AR. Moreover, they have positive perpeption of improving the quality of teaching and learning ESP through action research.