The significance of listening comprehension in learning English as a foreign language cannot be denied, as it forms a foundational basis for effective communication and language skill development. Proficient listening skills are essential not only for understanding spoken language but also for meaningful communication, grasping nuances, and interpreting contextual cues. Furthermore, listening comprehension serves as a cornerstone for vocabulary acquisition, grammar understanding, and cultural awareness, making it one of the most crucial aspects of language learning. This study investigates the effectiveness of the Duolingo mobile application in enhancing EFL students' listening comprehension within the evolving landscape of educational methods. Data collected from 39 third-year English major students at the School of Foreign Languages, Can Tho University, Vietnam, through comprehensive surveys and structured interviews highlighted the students' high appreciation for Duolingo's impact on their listening abilities within the Vietnamese educational context. Students emphasized the flexibility and engaging nature of Duolingo's listening features, which immerse learners in diverse real-life situations and provide opportunities for repetitive practice. Regular engagement in these exercises was considered essential for expanding vocabulary, improving grammar, and achieving deeper language comprehension in realworld contexts. Despite receiving positive evaluations, participants identified areas for improvement, particularly emphasizing the need for diversity in pronunciation and contexts within Duolingo's listening exercises to enhance effective communication. Moreover, they suggested improvements in feedback mechanisms to provide timely and useful feedback for language learning progression. In conclusion, while the Duolingo mobile application offers promising opportunities for enhancing EFL students' listening comprehension, addressing current limitations is crucial to optimizing their effectiveness. This study underscores the importance of using mobile language learning tools like Duolingo to meet the evolving needs of language learners in an education landscape increasingly driven by technology, where listening comprehension plays a vital role in the learning and language proficiency enhancement process.