This paper investigates the factors that affect the price of the shares of industrial companies listed on the Stock Exchange in Ho Chi Minh City (HOSE). The data used in this study are collected according to the date of publication unified consumer price index of the Central Statistical Office (on the 24th of the last month of the quarter) from 2012 to 2015. Using regression analysis showed that EPS and exchange rate (USD / VND) and interest rate correlated to the profitability ratio of the shares the price of gold and the rate of inflation measured by the consumer price index (CPI) has negative correlation to rate profitability of the shares.