The Fourth Industrial Revolution requires agriculture to apply e-commerce in promoting production and consumption. In particular, in the context of the severe situation of the COVID- 19 pandemic, which has increased consumer demand for online shopping, many industries have already transformed from offline business to online business. However, this form is quite new and not popular among farmers yet. This research, therefore, analyzes awareness and perception to apply e-commerce on agricultural products in Hau Giang province, Vietnam. The data was collected through a survey of 484 households, including 160 rice farmers, 164 lemon farmers, and 160 jackfruit farmers in Hau Giang province, Vietnam. Descriptive statistics, t-test, and ordered logistic regression were employed in the analysis. Research results reveal that local households have partly recognized some forms of e-commerce such as online sales (i.e livestream and Facebook), connecting with online businesses and stores to sell products, proceed to implement traceability for agricultural products. Although farmers’ skills and applicability are limited, the majority of them would like to apply e commerce to consume their products. Based on the analysis, this research recommends that local authorities should pay more attention to the consumption of agricultural products by providing training skills, technology knowledge and facilitating online business stores for farmers to participate.