The research focuses on managing information technology applications in master's degree education to enhance the quality and effectiveness of master's degree education management. From an overview of some relevant terms regarding managing information technology applications in master's degree education, this article proposes six measures for managing information technology applications in master's degree education at Can Tho University. The flexible application of these measures by the university will contribute to improving the effectiveness of information technology application management in master's degree education, thereby enhancing the quality of master's degree education to meet the high-quality human resource needs of society.