The objectives of this study were analysis of the secondary metabolite products from extract of marine
Penicillium citrinum strain ND7a which isolated from sponges at Ha Tien Sea, Kien Giang province, Vietnam. Sixteen bioactive compounds were identified in the organic solvent hexan-aceton and aceton-methanol. The identification of bioactive chemical compounds is based on the peak area, retention time, molecular weight and molecular formular. GC-MS analysis of Penicillium citrinum strain ND7a revealed the existence of the 9-Hexadecenoic acid, Hexadecane, n-Hexadecanoic acid, Heptacosane, Octadecane, 3-ethyl-5-(2-ethylbutyl), Tributyl acetylcitrate, 17-Pentatriacontene, Hexanedioic acid, bis(2-ethylhexyl) ester, Bis(2-ethylhexyl) phthalate (in organic solvent hexan-aceton) and Oxime-, methoxy-phenyl, 2-Hydroxy-gamma-butyrolactone, 7,9-Di-tert-butyl-1-oxaspiro(4,5)deca-6,9-diene-2,8-dione, Pentadecanoic acid, 14-methyl-, methyl ester, Hexadecanoic acid, 1-(hydroxymethyl)-1,2-ethanediyl ester, Stigmasterol, γ-Sitosterol (in organic solvent aceton-methanol).