Using survey data of 231 rural households suffering from saline intrusion in the Mekong Delta and descriptive statistical methods, the study analysed households’ perceptions of the impacts of saline intrusion. At the same time, the study analyses the adaptation actions that households take to cope with salinity intrusion. On that basis, research and develop a mechanism for the impact of salinity intrusion on rural household livelihoods. From there, propose appropriate solutions to help rural households in saltwater intrustion areas stabilize their livelihoods.