This study aimed to determine the effect of salinity on the survival rate and growth of whiteleg shrimp postlarvae reared using biofloc technology. The experiment included four treat-ments at different salinities: 10‰, 15‰, 20‰, and 25‰. Each treatment consisted of three replicates. Shrimps were reared using biofloc technology with a C/N ratio of 15:1 and additional sugar treatment. Shrimps were cultured in 500 L-tanks with a stocking density of 2,000 inds/m3. The initial weight of shrimp was 0.006 g. After 30 days of rearing, the growth rates of shrimp differed significantly among treatments (P < 0.05). The results showed that the length (4.54 ± 0.06 cm), weight (0.79 ± 0.04 g), and survival rate (91.5 ± 1.0%) were significantly greater (P < 0.05) for the shrimp reared in the treatment salinity of 15‰ compared to the other treatments. Therefore, rearing whiteleg shrimp at a salinity of 15‰ using biofloc technology is appropriate.