The objective of the study is to recycle fishpond sediment as fertilizer for vegetable cultivation in order to limit the discharge of sludge into the natural environment that causes water pollution. Research method: using pond bottom mud for raising snakehead fish and agricultural by-products to compost and then fertilize spinach, the study consisted of 2 experiments: (1) Composting organic fertilizer: by mixing sewage sludge and peanut shells (BT&VL) at the ratio of 10, 30, 50, 70 or 90% of the mixture. (2) Growing vegetables: using the best fertilizer after experiment 1 to grow vegetables according to 5 treatments combining inorganic fertilizers. organic and organic fertilizers in the ratio: 100% inorganic fertilizer (control), gradually reducing to 75%, 50%, 25% and 0%. Research results show that the highest nutrient concentration of manure found in CT4 is 30% of sewage sludge combined with 70% of organic by-products. The highest vegetable yield was obtained in NT3 when using 50% inorganic fertilizer and 50% organic fertilizer, the lowest yield was obtained in NT1 and NT5 when only inorganic or organic fertilizers were used. This finding can be considered applied to some other types of aquaculture sludge and other leafy vegetable crops.