The specialized group is the fundamental operational unit in the organizational structure of secondary schools, established and managed by the principal. It is the most important organization in implementing the specialized activities of the school. This article presents the current situation of the activities carried out by the specialized groups in high schools in Ninh Kieu district, Can Tho city. Through research, it has been found that the majority of school administrators and teachers highly value the importance of the specialized group’s activities. The content of the specialized group’s activities in high schools in Ninh Kieu district, Can Tho City, is assessed to be carried out regularly. The research results serve as a practical basis for proposing appropriate and high-quality management measures for the specialized group’s activities in high schools in Ninh Kieu district, Can Tho City