The study was conducted to determine the factors affecting the intention of people to separate garbage in Vinh Chau town, Soc Trang province, Vietnam by surveying 198 households. Cronbach's alpha analysis method, EFA analysis along with linear regression analysis were used in the study. The analysis results of Cronbach's Alpha index, KMO and Bartlett's test showed that the questionnaire data used in the study was high reliability and was suitable for EFA analysis. The results of linear regression analysis identified three factors including "subjective norm", "control of cognitive behavior" and "perceived level of garbage classification information" that had positive impact on intention of domestic solid waste classification of local people in Vinh Chau town, Soc Trang province. In which, "subjective norm" was considered to be the most influential factor on the intention to classify domestic solid waste in the study area. Besides, the intention of the people to separate the domestic solid waste was highly appreciated, but it has not been widely implemented in the locality. Therefore, the study proposes some governance implications based on the factors affecting the intention of people to classify household’s solid wastes. In particular, local authorities should pay special attention on propagating and disseminating policies and guidelines on information of domestic solid waste and implementing a model of waste separation at source.