The Mekong Delta, Vietnam, has a favorable position in terms of natural conditions and irrigation systems in agricultural cultivation, especially rice production. The focus on rice farming has contributed to the Mekong Delta owning the most extensive rice-growing land in Vietnam. The policies of the State and the region, together with the impact of climate change, have helped farmers in the Mekong Delta convert effective farming models on rice land, contributing to rising incomes for farmers, successfully implemented the Government's policy on restructuring crops and livestock. Research on crop transformation in agriculture – a case in Mekong Delta in Vietnam to generalize the situation and change the farming model on rice land of farmers. Research showed that farmers tend to change the structure of crops on inefficient rice land to adapt to climate change and bring high income to farmers.