Hydro-distillation was used to obtain the essential oil from pomelo (Citrus grandisL.) peels collected in Vietnam.The effects of extraction variables including size of material, temperature, extraction time, and water-to-material ratio on the yield of essential oil were investigated. In addition, to assess the quality of pomelo essential oil, the chemical composition was compared.The optimized conditions were as follows: material size of grind, temperature 120°C,water to material ratio 5 mL/g, and extraction time 105 min., respectively. The chemical composition of the pomelo oil was then determined by GC-MS, where components were identified, of which, limonene was the highest (97.1%). This method can be considered as a green method of extractionmethod as it is less energy intensive process and offers high performance.The results are expected to aid in justification of hydro-distillation in industrial applications and inrefining of extraction parameters.