This research aims to demonstrate the influence of psychological capital on job satisfaction and job performance of tour guides. The research data were collected using a convenient sampling method, with a sample size of 260 tour guides at famous destinations in Vietnam. The survey was focused on three famous destinations in Vietnam, including Ho Chi Minh City (108 tour guides), Can Tho City (72 tour guides), and Kien Giang Province (80 tour guides). By applying the structural equation modeling (SEM), the research results show that psychological capital has a positive influence on job satisfaction and job performance of tour guides. Additionally, job satisfaction is positively correlated with the job performance of tour guides. The research results emphasize the importance of positive psychological capital for the job satisfaction and job performance of tour guides. Moreover, the research results contribute to suggesting managerial implications for enhancing the job satisfaction and job performance of tour guides.