Elephantopus  scaberL. is a useful medicinal plant and has been used as a traditional medicine for vari-ous diseases in Asia. In this study, we completed and characterized the chloroplast genome ofE. scaberof which the length was 152,375 bp. This circular genome had a large-single copy (LSC, 83,520bp), asmall-single copy (SSC, 18,523 bp), and two inverted repeat regions (IR, 25,166bp). There were 80 pro-tein-coding genes, 30 tRNA genes, and four rRNA genes in the chloroplast genome ofE.  scaber.Phylogenetic analysis inferred from 80 protein-coding regions revealed a close relationship betweenE.  scaberandCyanthillium  cinereum(L.) H.Rob. and a sister relationship between Vernonioideae andCichorioideae subfamilies. The genomic data ofE.  scaberprovide useful information to explore themolecular evolution of not onlyElephantopusgenus but also the Asteraceae family.