Household hazardous waste is an important part of the domestic solid waste stream, which can cause significant harm to the health of families, communities, and the environment if not managed properly. The research was conducted to assess the current status of household hazardous waste generation and management in Long Xuyen City, An Giang Province. The study interviewed 100 households and collected hazardous waste over three months. The results showed that household hazardous waste reached 0.8395 kg/person/year, equivalent to about 228.97 tons of household hazardous waste each year, of which, 62.59% of them are bottles and jars with dangerous chemicals. The waste sorted by households was found to be inadequate, with 98% of households not separating hazardous waste from other regular waste. Only 68% of households have registered services for hazardous waste at the Long Xuyen City Hazardous Waste Treatment Plant. The other predominant waste disposal methods included improper burning and burial (accounting for 8%) and selling scrap materials (accounting for 24%). Although the residents in the research area exhibited good knowledge and positive attitudes toward household hazardous waste management, their practices regarding the management of such waste were found to be inadequate.