Rice is an important human crop and rice cultivation is threatened due to natural disasters, leading to negative effects on national and global food security. Natural disasters, such as tropical cyclones and saline intrusion, have dramatic influences in coastal regions. To investigate possible impacts of these disasters on rice cultivation, it needs an efficient tool to assess potential disaster impacts and a risk index is highly applicable. Therefore, this study aims at establishing a risk assessment of rice production in coastal areas under the effects of tropical cyclones and saline intrusion. We adopted the risk definition introduced by [1] in which risk is a function of hazard, exposure and, vulnerability. Multiple hazards of tropical cyclones and saline intrusion were indicated by their frequency and severity at some critical levels of 25%, 50% and, >50% rice yield reduction. Each hazard was weighted by its damage to rice yield. The exposure and vulnerability of rice crops are evaluated at different growing phases. The tropical cyclone hazard index was ranked high and very high in the wet season while the salinity hazard index was ranked very high in the dry season. Due to the combined effects of tropical cyclones and salinity, rice crop is highly susceptible during the reproduction phase and at the panicle initiation stage particularly. Based on the cropping calendar of My Xuyen, the period of October-November was the very high vulnerability period since it had the largest rice cultivable area and rice crops were at the reproduction phase. This result shows that rice crops are at high risk in October and November. Noticeably, saline intrusion reaches the highest level in April and May, but no risk is at this period because of no rice crop cultivated. This can reflect a measure to reduce risk by adjusting the cropping calendar.