This study attempted the extraction of essential oils (EOs) from orange peel, and optimized the experimental parameters of the microwave-assisted hydrodistillation process. Gas chromatography-Mass spectrometry was often used for the assessment of the chemical content of the natural oils collected. Optimal conditions for the extraction process consisted of the ratio of 1:3 peel/water, microwave power of 300W and duration of 45 minutes. These conditions gave the highest yield (2%). From the gas chromatographic results, five components were identified in the obtained orange peel EOs with Limonene being the major components (98.416%). Based on availability, orange peel is suggested as an economically viable source for limonene production. Obtained results are expected to aid in mitigation of environmental impact caused by agricultural wastes.