Utilizing a course book is one of the most popular teaching materials in every classroom. It plays an important role in both English teaching and learning and is considered one of the most efficient tools to examine the education quality. There have been many studies on the evaluation of course books in the world; however, up to present researchers find there has just few studies related to the evaluation of the course book LIFE for the General English course in the Vietnamese context. Thus, the study was carried out to find out how English as a foreign language (EFL) students would evaluate and use the course book LIFE (A2-B1) for General English courses. The participants of the study were 100 non -English major students of different classes at Bac Lieu University, Vietnam. The instruments used to collect data for the study were a 100- item questionnaire and the interviews with 7 random students participating in the questionnaire. The results revealed that most of the students had a positive evaluation on the course book; however, they had different strategies for their learning and use of the course book. The findings of the study suggested that EFL teachers should pay attention to their students’ evaluation to gain some insights in order that they would have flexible teaching methods and use of the course book to help their students improve English knowledge and skills in the future.