Four compounds, named ursolic acid (1), 1,3-dihydroxy-6,7-dimethoxyxanthone (2), luteoloside (3) and vitexin (4) were isolated from the whole plant of Eleusine indica (L.) Gaertn. by various chromatography methods. Its chemical structure was elucidated by NMR 1D and 2D experiments and compared with those published in literatures.