This paper examines economics majors' attitudes towards learning English for Specific Purposes (ESP) at a university in the Mekong Delta, Vietnam. Specifically, it investigates cognitive, emotional, and behavioral aspects of their attitudes towards ESP. Gender difference is also out into consideration. Data were collected from a questionnaire administratered on a total of 246 non-English majored students. The results showed that the respondents had positive attitudes towards learning ESP in cognitive, emotional and behavioral aspects. Moreover, the findings also indicated there was no statistically significant difference in attitudes towards learning ESP by gender. The study provides a theoretical basis regarding students' attitudes towards learning ESP in all directions.