Aims of the research were to: (i) survey the land fluctuations in the urban areas by application of satellite image – Sentinel 2; (ii) Assess the capability of using Sentinel-2 in urban management. The research carried out some methods such as: processing and images analysis to establish the land urban map (according Nguyen Van Trung, 2010); Statistic and compare to observe fluctuation; or design and calculate area on the map by GIS. The result show that: in Cai Rang district, Sentinel-2 images have interpreted and established urban land map with total precision is 88.88% in 2015, Kappa index is 0,78 whereas total precision is 86%, Kappa index is 0,72 in 2018. Besides, there is a rapid increase in the urban land use of Cai Rang district. In addition, Hung Thanh and Phu Thu are two urban regions have highest areas and fluctuation land use. In contrast, Ba Lang district has smallest urban area. In this paper, the result reminded that: Sentinel-2 is a high solution (10 m) which has a free satellite image and suitable for detail researches. However, the bad climate impressed the quality images. It is difficult to have a correct images same time. It’s necessary to add a new index so that improve the exacting research.