Socio-economic development in the Vietnamese Mekong Delta is shaped by a complex web of interacting and dynamic trends. Based on the analysis of statistical data, special reports, planning documents and scienti ? c literature, the chapter examines the key dimensions of such trends, paying particular attention to agricultural transformation, industrialization, migration and urbanization. It is argued that changes in these  ? elds have been producing ambiguous economic neteffects and socially strati ? ed development outcomes over the last decades. On the one hand, the agricultural sector in the Mekong Delta has been experiencing profound production gains due to de-collectivization, expansion, intensi ? cation and diversi ? cation. This has contributed to overall poverty reduction in the Delta and to the economic progress of the entire country. On the other hand, the Mekong Delta lags behind the national average in terms of many development indicators in the socio-economic sphere (e.g. education levels or housing conditions). Under stress from multiple economic and environmental pressures and risks, small-scale farmers increasingly have dif ? culties securing a minimum level of pro ? tability and a stable livelihood base. Rising inequalities, high incidences of landlessness, and labour migration, notably into urban areas, are among the most signi ? cant consequences. At the same time, industrial development falls short of earlier expectations. The Delta?s secondary and tertiary sectors are presently unable to suf ? ciently absorb the former agricultural labour force. As a result, strong outmigration occurs, most importantly to Ho Chi Minh City and its neighbouring provinces. Guided by development theory we argue that next to the neoclassical expansion of conventional capital stocks for fostering endogenous growth potentials, development in the Mekong Delta heavily depends on institutional factors, enabling social and economic development. Aspects such as the need for improved access to land or for extended education and professional training, more integrated planning, and intensi ? ed promotion of economic innovations are discussed in detail.