Real-Time Kinematic (RTK) GPS is generally used in industrial applications that require position accuracy to millimeters. However, RTK-GPS is employed at a high deployment cost of a local base station which requires high-cost dual-frequency GPS receiver module and antenna. The aim of this study is to evaluate the accuracy of a low-cost RTK-GPS system for future applications in the Mekong Delta such as precise farming, remote sensing, etc. In this study, low-cost single-frequency GPS receivers and antenna were used in a low-cost RTK-GPS setup. Static and kinematic positioning experiments were performed. Experimental results in kinematic positioning showed that the tracked positions of a slow moving rover aligned well with its moving route. The relative position accuracy of a still rover could be considered less than 0.2 meter. This indicates promising utilization of low-cost RTK-GPS systems especially in many agricultural and environmental applications in the Mekong Delta.