The objective of the current study was to (i) construct a fertilizer formula for plant pineapple in acid sulfate soil in Hau Giang and (ii) evaluate the capacity of the acid sulfate soil to supply nutrients (N, P, K, Ca, and Mg) that can enhance plant pineapple growth and yield. A completely randomized block design was applied with 8 treatments and 4 replications each. The treatments were as follows: (i) no fertilizing, (ii) NPKCaMg: full fertilization of N, P, K, Ca, and Mg, (iii) PKCaMg: fertilization omitting N, (iv) NKCaMg: fertilization omitting P, (v) NPCaMg: fertilization omitting K, (vi) NPKMg: fertilization omitting Ca, (vii) NPKCa: fertilization omitting Mg, and (viii) FFP: farmers’ fertilizer practice. The calculated fertilizer formula for plant pineapple in acid sulfate soil in Hau Giang was 488 N-359 P₂O₅-407 K₂O-1108 CaO-568 MgO kg ha^-1. The N, P, K, Ca, and Mg supplying capacities were 44.4, 11.9, 42.3, 10.2, and 13.1 kg ha^-1, respectively. Meanwhile, the group with SSNM fertilization increased growth and consequently enhanced plant pineapple yield by 30.2% higher than the group with FFP fertilization. The new recommended fertilizer formula should be applied to the indigenous soil for sustainable local pineapple cultivation.