The objective of the study was to analyze the factors affecting the decisions to outsource logistics services of seafood exporting enterprises in the Mekong Delta. Data was collected by questionnaires from 100 seafood exporting enterprises in the Mekong Delta using outsource logistics services. The study used exploratory factor analysis (EFA) and multivariate regression analysis. The research results identified four factors: (1) Strategy; (2) Costs; (3) Characteristics of the Logistics Process; (4) Characteristics of Logistics Providers, which had positive influence on logistics outsourcing decision of seafood exporters in the Mekong Delta.