This study was conducted to shed light on travel motivations of domestic tourists to Can Tho City, which would be used to help attract more visitors and develop local tourism. This study employs a five-level Likert scale to evaluate the significance of the travelers’ motivations, together with the Exploratory Factor Analysis (EFA) and Discriminant Analysis by using designed questionnaires to interview 140 local travelers visiting Can Tho city recently. As revealed in the findings, tourists coming to Can Tho City are likely to be influenced by seven travel motivations, which could be categorized into push motivations and pull motivations. The former includes (1) relaxation and self-affirmation, (2) prestige, (3) entertainment, (4) social contact. The latter comprises (5) accessibility and reasonable prices, (6) resources and entertainment, (7) history, culture, and gastronomy. Besides, the author also suggests some solutions based on the evaluations of the significance of the push and pull motivations