The article has studied the current status of managing self-study activities of students at Can Tho University of Medicine and Pharmacy, including the current status of managing students' self- study activity plans; Current status of managing the implementation of students' self-study activities; Current status of directing students' self-study activities; Current status of testing and evaluating students' self-study activities. The results of the above survey of the current situation are an important basis for researching and proposing measures to improve the effectiveness of managing self-study activities of students at Can Tho University of Medicine and Pharmacy