Article info.

ABSTRACT

Received date: 03/10/2015

Accepted date: 30/11/2016

Stability of folate at different pH (3 to 9) toward thermal (65 to 140°C) treatments was studied on a kinetic basis. Residual folate concentration after thermal treatment was measured using reverse phase liquid chromatography. A model to describe the temperature effect on folate degradation rate constant is presented with the degradation of folates followed first-order reaction kinetics. The estimated Arrhenius activation energy (E_a) values of folate thermal degradation were determined.

At all pH values studied, it was found that (i) folic acid and 5-formyltetrahydrofolic acid were more thermo stable than tetrahydrofolic acid and 5-methyltetrahydrofolic acid and (ii) all folates studied had the highest stability at neutral pH (pH 7.0) or alkaline pH (pH 9.2).

Keywords

Folates, thermal, kinetic,
stability, pH

Cited as: Thuy, N.M., 2016. Study on folate stability during thermal processing. Can Tho University Journal of Science. Vol 4: 87-94.